can semaglutide raise tsh levels Study: Patients With Hypothyroidism Who Lost Weight on Saw Decreases in Semaglutide and thyroid medication :
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Doan .E., Kukonmaz .M., Koc G., Aypar E., ulha C Case series: exposure to glucagon-like peptide-1 receptor agonist in the first trimester of pregnancy in two siblings

The clinical consensus is that if semaglutide alone isn't working, dose escalation or genetic testing to find alternative compounds (such as tirzepatide) is safer than adding a second drug class
