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Current evidence suggests limited transfer of GLP-1 medications into breast milk, but clinical data remains sparse

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Five clinical trials in type 2-diabetic subjects (SURPASS 15) have shown that tirzepatide at 515 mg per week reduces both HbA1c (1.24 to 2.58%) and body weight (5.411.7 kg) by amounts unprecedented for a single agent

These findings suggest that TZP mitigates T2DM-associated hepatic injury by favoring mitochondrial fusion, alleviating oxidative stress, and protecting tissue integrity
In 2025 we saw label expansions for semaglutide and tirzepatide, underscoring a trend toward whole-body health