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In contrast to T1Rs, only one type of bitter taste receptor is expressed per taste cell pointing towards the enormous role to distinguish diverse bitter compounds in contrast to just detect nutritious, sweet and savory food [33]

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Increases concentrated early after medication initiation suggest detection of pre-existing nodules (surveillance), not new cancer induction
However, it also has potent side effects and needs a commitment to long-term use and lifestyle modifications

Focus on Foundational Science: The primary goal should be to expand scientific understanding through rigorous research, not to bypass established regulatory pathways
