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Am J Ophthalmol 2024;265:39-47
Approximately 25% of the weight lost on tirzepatide was lean mass rather than fat, and in semaglutide trials (STEP 1 DXA subset), that proportion may approach 40%

Subgroup analysis in patients with positive baseline C-peptide levels showed a more robust reduction of HbA1c (i.e., 0.69-0.83%) on GLP-1RA in this group (57)
Even though weight loss reaches a plateau after about a year or so, people who take a GLP-1 RA for weight loss might still prefer to stay on it for the long term
Virginia Medicaid changed criteria, limiting coverage to individuals with a body mass index (BMI) greater than 40 or those with a BMI greater than 37 with weight-related comorbidities (defined as hypertension, type 2 diabetes, or dyslipidemia) effective July 1, 2024

[DOI] [PubMed] [Google Scholar] 6.Gerstein HC, Miller ME, Byington RP, Goff DC, Jr, Bigger JT, et al