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SGLT2 inhibition reprograms systemic metabolism via FGF21-dependent and -independent mechanisms
Adult obstructive sleep apnoea
The primary endpoint will be bodyweight change (week 80 and 104), change in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in the OA subset, and change in Apnoea-Hypopnea Index (AHI) in the OSA subset
Have regular follow-ups to monitor labs and adjust the plan
S., Woldeyohannes, H
