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Serious but Rare Side Effects Less common but more serious side effects can include: Pancreatitis Severe abdominal pain that requires immediate medical attention Gallbladder problems May cause pain in the upper right abdomen Severe gastroparesis Stomach paralysis that can be dangerous Kidney problems Changes in urination or swelling Severe allergic reactions Reported in less than 1% of patients Diabetic retinopathy In people with diabetes Possible risk of thyroid cancer Only seen in animal studies and not in humans Low blood sugar Particularly if taken with other diabetes medications like insulin These serious side effects occur in less than 1% of patients but require immediate medical evaluation if symptoms develop

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All three pathways are now meaningfully engaged

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Liu W, Luo Z, Zhou J et al

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