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Knockout of SLC5A2, which encodes the protein of SGLT-2 in rodents, reportedly caused polyuria, hyperphagia, increased glucosuria, and decreased aldosterone, and increased circulation renin
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[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Yamaguchi S., Franczyk M.P., Chondronikola M., Qi N., Gunawardana S.C., Stromsdorfer K.L., Porter L.C., Wozniak D.F., Sasaki Y., Rensing N., et al

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