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In addition to effects on weight and blood glucose control, early laboratory studies in mice suggest that GLP-1 RAs might work through additional biological mechanisms ( 10 , 11 )

Free T3 (FT3) is an active form of thyroid hormone, whereas Reverse T3 (RT3) binds its receptors to FT3 to slow down metabolic processes

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These factors are produced by selective posttranslational modification of proglucagon , a 160-residue peptide expressed by the -cells of the pancreas, K and L cells of the small intestine