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Further, observed improvements can be due to optimised formulations or excipients, rather than using a microneedle, which is not often disentangled in study designs
All treatments require evaluation by a licensed provider

Hormonal factors can blunt the response

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Researchers also watch appetite, glycemic markers, lipids, waist circumference, liver fat, blood pressure, and safety labs

doi: 10.1523/JNEUROSCI.3542-07.2007
