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No significant drug interactions have been identified between GLP-1 receptor agonists and standard autoimmune medications including methotrexate, biologics (TNF inhibitors, IL-6 inhibitors), JAK inhibitors, or hydroxychloroquine

By contrast, a recent clinical trial by Eli Lilly tracked nearly 400 subjects who switched from shots to Foundayo, and found that on average, they maintained most of their weight loss after 52 weeks

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Novo has already extended its original patent on semaglutide to 2031

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