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Description
Patients with variants linked to rapid response may benefit from different timing or dose-escalation pacing, while those with lower genetic sensitivity often need patience and consistency as medication accumulates

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Cycle in trials 24-week treatment periods in both Phase 2 (Astrup 2008) and the Mexican Phase 3 study

Analgesic Outcome: Diminishes peripheral sensitization, easing inflammatory and neuropathic pain without disrupting normal sensation

Summary and conclusion The GLP-1 has emerged as a therapeutic powerhouse, far exceeding its initial recognition as a gut hormone
