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Description
Studies show that patients with these complications may require 2030% higher doses to achieve the same therapeutic effect as those with healthy injection sites

Semaglutide produced roughly twice as much weight loss as previously-available drugs (for example orlistat, which doesnt alter appetite but stops the body absorbing fats from food)

Aging Cell 9 , 304312 (2010)

But lets zoom out a moment

[DOI] [PubMed] [Google Scholar] 874.Torgerson JS, Hauptman J, Boldrin MN

Patients with ESRD have a high burden of comorbidities
