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Description
Safety: GI AEs: 74% vs 42% AE discontinuation: ~7% vs ~6% Clinical takeaway: High-efficacy weight loss with a once-daily oral GLP-1RA potentially expanding uptake for patients who prefer to avoid injections

Different classes of drugs have been used and tested, but the resolution of PPH remains a challenge for physicians and patients

Weight gain after gallbladder removal is a common experience
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No oral tirzepatide is FDA-approved in 2026 (no tirzepatide pill, tablet, or drops)
