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GLP-1 medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have transformed type 2 diabetes and weight management

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Metformin has been shown to regulate steroidogenesis through a number of different mechanisms and cell types

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Individual results varied widely - some participants lost significantly more, some lost less, and some did not lose substantial weight even on the highest doses