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Description
Around 93 patients (11.6%) had upper GI symptoms such as nausea, vomiting, and abdominal pain
therefore, the development of new therapeutic strategies has been sought
In addition to the effect on food intake reduction and glucose-stimulated insulin secretion, GLP-1 also acts to delay gastric emptying therefore aiding satiety and glycaemic control (42)
Microdosing follows a research-supported model that uses lower initial concentrations of GLP-1 compounds to minimize gastrointestinal side effects while maintaining metabolic benefits
In this metabolic state, the body shifts from glucose to fat-derived ketone bodies as its primary fuel source
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