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GI tolerance Some patients experience persistent nausea or constipation on semaglutide

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Figure 4 2.1 JAK inhibitors Recent research has increasingly concentrated on the JAK-STAT signaling cascade, yielding innovative therapeutic approaches for improving IBD management ( Currently, several pan-JAK inhibitors and selective JAK inhibitors, including novel TYK2 inhibitors, underwent recent or on-going development at different Phases for IBD treatment