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However, following a gradual dose escalation schedule, maintaining adequate B vitamin and mineral intake, optimizing sleep quality, managing stress, and monitoring for early sensory changes during dose increases may help reduce risk or enable early detection

Gould notes, they havent been fully demonstrated in human tissue or large-scale trials. Whats more, it can be hard to tease out the influence of GLP-1s from that of age and hormones, which can similarly undermine our tissues

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References [1] Helmstadter, J., et al

Additionally, there may be some limited risk to healthy athletes

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Kulkarni C.A., Brookes P.S