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Animal vs human study limitations Much of the microbiome research on semaglutide comes from rodent models

doi: 10.1002/oby.23086

The blood pressure-lowering effects likely result primarily from weight loss, which reduces cardiac workload and peripheral vascular resistance , leading to decreased blood pressure through hemodynamic changes

These are not minor observations

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Those with diabetes should monitor blood glucose levels before and after donation and maintain levels within their prescribed range throughout the donation process