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Available from: European Medicines Agency (EMA) (2023) Victoza

doi: 10.1210/endo-125-6-3109

As most of the available evidence stems from in vitro and preclinical studies, there remains a need for long-term and in vivo research to substantiate these findings and assess their translational relevance

AND Drafting the work or revising it critically for important intellectual content

Ex-4 treatment upregulates the expression of the proteins critical for mitochondrial biogenesis, including peroxisome proliferator-activated receptor- coactivator-1 (PGC-1), nuclear respiratory factor-1 (NRF-1), and transcription factor a, mitochondrial (Tfam)

All combination groups that included DAPA achieved suppression of this effect