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Notably, glucagon-like peptide-1 (GLP-1)-based drugs are being successfully used to control glucose levels in patients with diabetes mellitus

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GLP-1 receptor agonists have demonstrated significant weight loss results in clinical trials, with patients losing 15-22% of body weight over 68 weeks

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Retatrutide hit 28.3% weight loss in the May 2026 trial

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Semaglutida 1.34 mg/mL solucin inyectable IMSS

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These adaptations position irisin as a promising therapeutic target for preventing metabolic disorders and optimizing exercise protocols

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