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State of type 1 diabetes management and outcomes from the T1D exchange in 2016-2018

Roglic, G., Unwin, N., Bennett, P

Within the pancreas, GIP and GLP-1 together promote -cell proliferation and inhibit cell death, thereby resulting in pancreatic -cell mass-increase, while GIP enhances postprandial glucagon response and GLP-1 suppresses it [9, 10]

Mice with Y2R knockout in the hypothalamus have increased osteoblastic activity, mineralization rate, and bone mass, indicating that Y2R normally plays a catabolic role in stimulating cortical and cancellous bone formation [77]

Always consult your prescribing physician before altering your diet, taking new medications, or adding supplements to your GLP-1 regimen

165,166 The nervous system also modulates ghrelin secretion, as sympathetic nerve excitation stimulates ghrelin secretion from the GIT