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3 The agencys decision will have tremendous implications across the nation for patients and physicians, as well as the outsourcing facilities that made an enormous investment to meet patient demand in light of product shortages and delays. Gaps in Access Fuel Legal Pushback The plaintiffs in the lawsuit accused the FDA of ignoring supply realities on the ground
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Early satiety (feeling full after a few bites)

The answers ranged from enthusiastic endorsements to complete dismissal

Patients with GI sensitivity: While orforglipron's GI side effect profile is broadly similar to injectable GLP-1s, the daily oral dosing means the GI tract is exposed to the active compound on a different kinetic schedule than weekly injections
