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A recent post-hoc analysis of SURPASS-3 (NCT03882970) in adults with T2DM reported decreases in fat mass and muscle fat infiltration (MFI) accompanying weight loss [65], suggesting potential improvements in muscle quality that may be especially promising for older adults
What makes these medications conceptually coherent, beyond the individual findings, is that they fit naturally with a view of addiction as a disorder of dysregulated reward, stress, and self-regulation
Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors