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GLP-1 medications like semaglutide and tirzepatide show mixed effects on gastrointestinal symptoms, with potential benefits for some IBS patients but also the risk of worsening symptoms in others

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June 6, 2025 A large retrospective review of more than 100,000 patients found the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in moderate peripheral artery disease (PAD) is associated with a decreased rate of cardiovascular events, major limb events and inpatient admissions