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doi: 10.1038/361031a0 121 RebosioCBalbiMPassalacquaMRicciarelliRFedeleE

Currently available anti-obesity medications have shown a modest weight reduction of approximately 5% compared to a placebo when used over the long term

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In particular, the administration of empagliflozin in individuals with prediabetes or diabetes was associated with the amelioration of glycemia and insulin sensitivity and with increased -hydroxybutyrate (BHB) levels