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Medline and Embase were searched up to 21 November 2025 for randomized controlled trials comparing OMMs versus placebo or active comparators in adults

The recommended starting dose for semaglutide is 0.25 mg weekly for the first 4 weeks, followed by gradual dose escalation to reach the maintenance dose

This can lead to serious symptoms like nausea, vomiting, pain, and even hardened food masses called bezoars

CBS News' Dr

At his highest, he weighed 540 pounds
