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Mauer M, Zinman B, Gardiner R et al (2009) Renal and retinal effects of enalapril and losartan in type 1 diabetes (RASS)

Weight loss reduces the mechanical load on bones, which can lead to lower bone density and, in some people such as those who are postmenopausal, as well as people over age 65 an increased risk of fracture

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The MHRA and EMA include pancreatitis warnings in prescribing information, though current evidence suggests benefits generally outweigh risks in appropriately selected patients

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