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The lack of a head-to-head comparison means the 46% figure should be interpreted as a retrospective analysis rather than evidence from a controlled trial
Within the NHS, Wegovy is offered for weight loss through specialist weight management clinics

Diabetes Care 33 , 23492354 (2010)

Expansion Across Key Indication Obesity / Weight Management: Orforgliprons Phase III trial ATTAIN-1 in non-diabetic obese or overweight adults (with weight-related medical conditions) showed clinically meaningful weight loss (up to ~12.4%) vs placebo over ~72 weeks

Rybelsus is approved by the US Food and Drug Administration (FDA) to treat type 2 diabetes

If your weekly dose is 10mg, you are currently getting all 10mg in one shot on one day
