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NIT-1 cells treated with PA+Ex-4 and PA+GW showed enhanced GSIS capacity, increased PPAR expression, decreased UCP2 expression and ADP/ATP ratio, and improved mitochondrial DNA content and mitochondrial membrane potential compared with those treated with PA alone, whereas the opposite results were observed in the PA+GSK group

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Shares in Amgen fell on Tuesday after they announced the results of a trial for their weight loss drug MariTide.