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Adherence in trials is artificially high for instance, 92.8% of patients in a 2-year semaglutide trial completed the study (source)

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and it is becoming increasingly recognized that body mass index (BMI) is not a great marker for malnutrition or sarcopenia since it does not account for proportions of weight lean mass, fat mass and/or fluid mass (4)

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Originally developed for the treatment of diabetes, now they are being lauded for their weight loss benefits

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Treating too early may lead to additional laxity later if your body continues to change

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