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Recently, multiple case reports and studies indicating safety risks for these medications and their use in patients planning to undergo general anesthesia have been published, as retained gastric contents can lead to intraoperative aspiration

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However, there was no significant difference in adverse CVEs or all-cause mortality when compared with those taking SGLT2 inhibitors

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We subsequently developed an in vivo technique to assess gut hormone release into the portal vein following colonic infusion of propionate