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The most commonly reported side effects are mild gastrointestinal symptoms, particularly during the initial days of supplementation

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Ethical approval This article is based on previously conducted studies and does not include any studies with human participants or animals conducted by any of the authors

A separate analysis estimated that roughly 45% of weight lost was lean tissue

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The standard titration schedule for semaglutide involves starting at a low dosetypically 0.25 mg weekly for the first four weeksand gradually increasing every four weeks until reaching the maintenance dose