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Description
This study aimed to develop and validate a sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of tirzepatide in rat plasma and to characterize its pharmacokinetic profile
Following intravenous injection (0.05 mg/kg, n=5), plasma concentrations of liraglutide decreased monoexponentially with an average half-life of 3.67 h
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