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Description
Xu J, Wang S, Wu H, Chen D, Han J, Lin Q
Kamboj AK, Katzka DA, Vela MF, Yadlapati R, Ravi K
The story of GLP-1 medicines has taken decades and begins with the venom of a lizard, and the regulation of blood sugar
As shown in Scheme 12
61 It exhibited a dose-dependent increase in intracellular cAMP levels in CHO cells expressing the human GLP-1 receptor
140,147,153,155,159 However, statins are known to exhibit high interindividual variability in terms of pharmacokinetics, and GLP-1 RA administration did not affect the lipid-lowering effect of statins in clinical studies, indicating minimal clinical significance
