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Description
I didnt even know I was microdosing when I was playing around with doses of my own accord
Dose escalation typically occurs gradually to minimise gastrointestinal adverse effects, which are the most common side effects of GLP-1 therapy
Some sensitive patients may benefit from microdosing (below 0.25 mg) or customized compounded formulations to improve tolerance
Unlike most peptide therapies, which target receptors in the pituitary or in soft tissue, MOTS-c works at the cellular energy level: it activates the AMPK pathway, regulates how mitochondria handle metabolic stress, and translocates into the cell nucleus to influence gene expression that controls metabolism
People on GLP-1s can run into constipation, dehydration, low fiber intake, and low micronutrient intake because total food volume drops
They're incredibly effective, helping many achieve significant health improvements
