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While higher doses (e.g., 20mg) are studied for maximal weight loss, the 10mg formulation provides an ideal concentration for dose-response analysis, receptor saturation studies, and mechanistic investigations into the contribution of each receptor subtype

But as you lose weight, you also lose muscle mass and connective tissue, which can cause that droopy look

The FDA approved CV risk reduction as additional indication for Wegovy and obstructive sleep apnoea for Zepbound

Results from a 20-week phase 1b clinical trial showed that a once-weekly dose of 2.4 mg cagrilintide in combination with an equal dose of semaglutide, collectively termed cagrisema, achieved up to 17.1% weight reduction in the obese population

Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jdar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML, et al

Most patients experience shedding 2 to 3 months after starting treatment, with regrowth beginning once weight stabilizes