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Whilst all GLP-1RAs use has increased, the largest change was seen in patients using tirzepatide and semaglutide ([figure 1B][1])

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Supresa Saffron Extract: Standardized to 0.3% safranal, this extract has been associated with a 69% decrease in hunger and a 55% reduction in snacking events over an eight-week period

On the flipside, there are challenges: for example, concerns about cost to healthcare systems and equity of access for patients with the greatest unmet needs, or the possible impact on Medtech currently used by patients suffering from obesity related conditions for example knee replacements for overweight patients with eroded joints or CPAP machines for sleep apnoea, a complication of obesity

Learn how they work, who theyre for, and the truth about microdosing.

This central action modulates appetite-regulating neurons, leading to reduced food intake and increased satiety