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meta-analysis: OR = 0.90, 95% CI [0.741.09]), and autism (FinnGen: OR = 0.42, 95% CI [0.320.54]

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These impacts included improved cardiovascular benefits, less joint pain, lower cholesterol and blood pressure, improved mood and energy levels and more

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For the cardiovascular outcomes, combination therapy demonstrated a significantly lower risk of hospitalization for heart failure compared to SGLT-2i monotherapy (RR = 0.37, 95% CI 0.19

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There is a potential for more serious side effects, but they are rare

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The author, Jin-Kui Yang, did not participate in the journals review of this manuscript or related decisions

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For someone starting at 250 pounds, a 22.5% reduction means losing over 56 pounds

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