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The table below summarises the quality signals

In the 1960s and 70s, scientists were puzzled by the observation that oral glucose caused a much greater insulin response than intravenous glucose

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Am J Physiol Endocrinol Metab (2011) 301(2):E31725.10.1152/ajpendo.00077.2011 133 FengRQianCLiuQJinYLiuLLiSet alExpression of sweet taste receptor and gut hormone secretion in modelled type 2 diabetes

N Engl J Med 2020

At this point, it is interesting to mention that also type 2 diabetes mellitus has been related to dysgeusia and altered taste thresholds [137]
