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How they work Zepbound and Wegovy work by mimicking natural gut-brain hormones that regulate hunger and fullness

The trial reached 2 primary endpoints, and the data had statistically significant differences: The main statistical methods showed that in all randomized patients, after 68 weeks of treatment, the SC semaglutide 2.4 mg + IBT treatment group lost 16.0% from the average baseline weight of 105.8 kg, and the placebo + IBT group lost 5.7%

Semaglutide is typically started at a low dose and titrated gradually upward to minimize side effects, which most commonly include nausea, mild digestive discomfort, and fatigue, particularly in the early weeks of treatment

Mullur, N., Morissette, A., Morrow, N

These programs are designed for different people

GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and dulaglutide (Trulicity) work through multiple mechanisms to control blood glucose and reduce appetite