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Oral glucose challenge and GLP-1 measurement Oral glucose challenge and plasma GLP-1 measurement were conducted 24 weeks after the initial treatment in DIO mice

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For example, the P5 exenatide analogue is biased to reduce the recruitment of -arrestin, resulting in better long-term hypoglycemic effects than those shown by exenatide, under the precondition that P5 has less cAMP activity

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