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Cardiovascular and kidney benefits of SGLT-2is and GLP-1RAs according to baseline blood pressure in type 2 diabetes: a systematic meta-analysis of cardiovascular outcome trials

Participation in a regulated clinical trial remains the only currently legitimate route to accessing retatrutide in the UK, and eligibility is determined by the trial protocol rather than standard prescribing criteria

Jger R, et al

The response to GLP-1 analogues can vary from person to person

We need to be mindful of how much to push

Glucagon-Like Peptide-1 Receptor Stimulation Increases GFR and Suppresses Proximal Reabsorption in the Rat
