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A 12-month routine may be appropriate for individuals focused on long-term metabolic support and lifestyle integration

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Cardani said drug-induced weight loss also comes with a drop in muscle mass and that patients who go off the drug tend to regain fat, though not muscle mass

Even when insurance approves tirzepatide, out-of-pocket costs can reach $200-$500 per month depending on deductibles, copayment structure, and whether the dose level qualifies as a specialty pharmacy tier

Both groups were instructed to take the medicine, a reduced-calorie meal plan, and increased physical activity