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If GLP-1 does enhance insulin actions and/or mediates direct effects in these tissues then the receptor(s)/mechanisms that mediate these effects are currently unclear

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A new genetic study suggests that higher levels of the hormone dehydroepiandrosterone sulfate (DHEA-s) are associated with a shorter lifespan in men, but show no significant effect on the lifespan of women

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If the only reason for treatment is acute ischemic stroke neuroprotection, the evidence base is still investigational and should be tested with stroke-specific protocols rather than borrowed from diabetes and obesity trials

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