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Interestingly, GLP-1 receptors are also found on pancreatic delta cells, producing somatostatin, an inhibitory hormone, further dampening glucagon secretion (53)

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[4] [5] The lipid improvements with GLP-1 therapy are generally proportional to the degree of weight loss achieved, and individual responses vary considerably

This effect may be mediated through central neural pathways as has been established for the action of GLP-1 to inhibit gastric acid secretion (52)