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Description
What is EBM

While safety within the phase 3 program is sufficient for marketing authorization (although the risk of cardiovascular events should not exceed a hazard ratio of 1.8 according to a guidance document that was released by the FDA at that time), it is the post-marketing phase in which rare adverse events and any other potential safety risks are identified or resolved

In clinical trials, tirzepatide achieved up to 18% weight loss compared to semaglutide at 12%

Among those with preexisting substance use disorders, GLP-1 takers had lower risks of hospitalization, overdose and suicidal ideation
This suits people focused on maintaining progress rather than pushing for further weight loss

At lower doses of Ozempic, weight loss is more modest
