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Obesity and metabolic conditions are among the most urgent health challenges worldwide , affecting over one-third of adults and contributing to diabetes, heart disease, and fatty liver disease

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10.1016/j.ijpharm.2023.123549 [DOI] [PubMed] [Google Scholar] 86.Lee SO, Kuthati Y, Huang WH, Wong CS (2024) Semaglutide ameliorates Diabetic Neuropathic Pain by inhibiting Neuroinflammation in the spinal cord

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More broadly, some reviews have suggested a conservative class-level washout approach of at least 4 weeks where direct evidence is lacking, although this should not replace molecule-specific label guidance (154)