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Description
Using an integrated ligand and structure-based virtual screening pipeline, explicitly combining complementary ligand-based descriptors, multi-fingerprint similarity, electrostatic similarity, pharmacophore modeling, and multi-conformation docking under a consensus-driven selection strategy, we were able to identify three chemically distinct classes of GLP-1R agonist candidates: GQB47810, a non-peptidic molecule
Semaglutid ve tirzepatid gibi GLP-1 zayflama ilalar etkili olmakla birlikte, GLP-1 ilalarnn yan etkileri, zel olarak hazrlanm GLP-1 ilalar ve sahte Ozempic gvenlik risklerini artrmaktadr.
Because GLP-1 also has potential anti-inflammatory properties, it can contribute to a healthier gut lining, thus preventing gastrointestinal problems in the long term
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