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Clinical research on HFrEF patients shows that GLP-1 agonists enhance left ventricular ejection fraction (LVEF) while reducing fibrosis according to preclinical investigations although clinical trial data for liraglutide remains neutral in FIGHT and LIVE [59,60]

Similarly, mml-1 / mxl-2 regulates gonadal longevity but does not affect the pha-4 /FOXA expression or DAF-16/FOXO nuclear localization (Lapierre et al, 2011

(2009) Improved treatment satisfaction and weight-related quality of life with exenatide once weekly or twice daily

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