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Description
In animal studies, GLP1-agonists were associated with reduced fetal weight and/or growth, delayed ossification and skeletal variants, usually associated with a reduction in maternal weight gain and decreased food consumption

Retatrutide already covers GLP-1, GIP, and glucagon receptors

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The synergy comes from GLP-1 reducing hunger while IF creates structured caloric restrictionneither strategy alone may achieve these results without the other
[PubMed] [Google Scholar] Hareter A

Although semaglutide lowered the overall risk of MACE, it did not significantly reduce the incidence of nonfatal stroke or heart failure hospitalizations
